How The Endocannabinoid System Affects Homeostasis In 2 Critical Areas Of Our Body
- Henry Johnson
- Jan 24, 2018
- 2 min read
We are advocating for CBD infused products and medical marijuana, but before we do any of that, we must know everything about the cannabinoid system of our own body.

The endocannabinoid system remained under the sheets for very long and it was only after the latter 20th century that we found out about its existence in our body. It was only after the discovery of ‘Anandamide’ and ‘2-AG’, the two cannabinoids produced in our body, that there are also two receptors making an entirely a new system in the body.
Although we were completely unaware of its existence, we can’t deny its importance as the ECS plays a huge role in keeping our systems in check (Homeostasis). The communication between the brain and different organs through neurons and cells is regulated by the ECS. In fact, the ECS is responsible for maintaining balance in all the crucial systems and organs of our body. Here, let’s discuss three of them!
Central Nervous System
The Central Nervous System comprises of two organs, the brain, and spinal cord. Of course, it also includes the neurons, proteins, and receptors which are like data packages between the brain and spinal cord. Brain transfers the information to the spinal cord which then forwards it to the different body parts. Now, CNS is associated will all the voluntary and involuntary actions which make the homeostasis inevitable.
CB1 receptors of the ECS are scattered all over the CNS regulating the flow of information between the brain and our body. In case of the lack of endocannabinoids, it is possible that this communication between the brain and body via spinal cord may get affected which then leads to disease.
Intestinal Tract and Immune Cells
The other cannabinoid receptors CB2 are present all over the gastrointestinal tract which is 80% immune cells. It has CB1 receptors as well. Thus, it can be said that CB2 is largely located in the immunity system. The endocannabinoid system regulates your gut-brain and immune system-brain connection through the gut-brain axis.
The feeling of being full, or triggering an allergic response to foods, the amount of acid secretion in the stomach, etc. are all regulated by the ECS. The homeostasis in the intestinal tract and immune system requires a healthy ECS.
Apart from these areas, CB1 and CB2 receptors regulate almost all the processes and systems of our body including the peripheral nervous system, respiratory system, endocrine system, etc. Each of these systems and processes can be affected adversely in absence of cannabinoids. Taking the phytocannabinoids externally can work as CBD is said to have the same affinity to CB2 as 2-Ag has and THC to Anandamide.
There is now an array of options for consuming CBD while the same cannot be said about THC as you have to be a certified patient for its consumption. Several manufacturers have introduced amazing products such as CBD gummies, some of the best CBD capsules, CBD infused drinks, terpenes, oils, wax, dabs, etc. which you could easily avail from online stores.
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